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MIA2 (基因名), Melanoma inhibitory activity protein 2 (蛋白名), MIA2_HUMAN.
产品名称:

Human MIA2/ Melanoma inhibitory activity protein 2 ELISA Kit
黑色素瘤活性抑制蛋白2

货号:

E13472h

商标:
EIAab®
监管等级:
别名:

CTAGE family member 5 ER export factor, Meningioma-expressed antigen 6/11, CTAGE5, MEA11, MEA6, MGEA11, MGEA6

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.176ng/mL
特异性:
Natural and recombinant human Melanoma inhibitory activity protein 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Human MIA2 ELISA Kit
规格 & 价格: cart
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Human MIA2 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤7.3%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤10.7%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

94

88-100

Plasma

96

90-102

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

88-99%

107-117%

111-120%

106-115%

EDTA plasma(n=5)

99-109%

88-101%

102-112%

95-107%

heparin plasma(n=5)

101-112%

 

100-109%

107-107%

99-109%

 

通用注释


亚单元:
Interacts with MIA3 (PubMed:21525241, PubMed:25202031, PubMed:27138255, PubMed:27170179). Interacts with the COPII coat subunits SEC23A, SEC23B and maybe SEC24C (PubMed:21525241, PubMed:27551091). Interacts with PREB; recruits PREB to endoplasmic reticulum exit sites (PubMed:25202031, PubMed:27170179). Interacts with APOB (PubMed:27138255).


功能:
Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum (PubMed:27138255, PubMed:21525241, PubMed:25202031, PubMed:27170179). Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum (PubMed:27138255). Thereby, may play a role in cholesterol and triglyceride homeostasis (By similarity). Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites (PubMed:21525241, PubMed:25202031, PubMed:27170179).


亚细胞位置:
Endoplasmic reticulum membrane Single-pass membrane protein Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER).


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