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Mgat4d (GeneName), Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D (ProteinName), MGT4D_RAT.
Product Name:

Rat Mgat4d/ Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Glycosyltransferase 54 domain-containing protein, GL54D

Detection Method:
ELISA
Specificity:
Natural and recombinant rat Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Rat Mgat4d ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
May self-associate; specifically in the endoplasmic reticulum prior to its translocation to the Golgi. Interacts with MGAT1, MGAT3 and MAN2A2; may interact with MGTA1 specifically in the Golgi.


Function:
May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.


Subcellular Location:
Golgi apparatus membrane Single-pass type II membrane protein Endoplasmic reticulum membrane Single-pass type II membrane protein


This product has not yet been referenced specifically in any publications.

[1].
"GnT1IP-L specifically inhibits MGAT1 in the Golgi via its luminal domain."

[2].
"A testis-specific regulator of complex and hybrid N-glycan synthesis."

[3].
"ELMOD2 is a candidate gene for familial idiopathic pulmonary fibrosis."

[4].
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."

[5].
"Genome-wide association with select biomarker traits in the Framingham Heart Study."

[6].
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."
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