MGAT4D (GeneName), Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D (ProteinName), MGT4D_HUMAN.
Human MGAT4D/ Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D ELISA Kit
N-acetylglucosaminyltransferase MGAT1 inhibitory protein, GlcNAcT-I inhibitory protein
Natural and recombinant human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
May self-associate; specifically in the endoplasmic reticulum prior to its translocation to the Golgi. Interacts with MGAT1, MGAT3 and MAN2A2; may interact with MGTA1 specifically in the Golgi.
May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.
Golgi apparatus membrane Single-pass type II membrane protein Endoplasmic reticulum membrane Single-pass type II membrane protein
MRTKQVNLLI | TLVAVALFSF | SCFSIYRITQ | TNNQLINCRN | HILEFKENML |
HLRNKTEKNT | QEMMKVLNR | MKYEITKREI | LSGNLVAQKA | DILNKNETVS |
NTFEDLKFFF | PHLRKEGRIY | P DVIIGKGK | TGVSFALGIS | TVNRGNYSYL |
KQTLTSVVSR | MTLSQEKDSV | VIVLVADSNE | DY LHSVVKM | ITKKFKRQVR |
SGSLEVISIP | AFLYSSMLNA | KHLAEASQKL | ASWRIKQVLD | FCI LLLYAQ |
PKAKYYLQLE | DDIIAKEMYF | TKITDFVGNI | SSNNWFFIEF | SMLGFIGKLF |
RSED LTHFV | RFFLMFYKEK | PIDWLLNDIF | QVKVCDAGED | LRNCMKRKKQ |
IRIQYKPSLF | QHVGI HSSF | PRKEQYEKKI |
This product has not yet been referenced specifically in any publications.
"GnT1IP-L specifically inhibits MGAT1 in the Golgi via its luminal domain."
"A testis-specific regulator of complex and hybrid N-glycan synthesis."
"ELMOD2 is a candidate gene for familial idiopathic pulmonary fibrosis."
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
"Genome-wide association with select biomarker traits in the Framingham Heart Study."
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."
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