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Mgat4b (GeneName), Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (ProteinName), MGT4B_MOUSE.
Product Name:

Mouse Mgat4b/ Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb, GlcNAc-T IVb, UDP-N-acetylglucosamine: alpha-1, 3-D-mannoside beta-1, 4-N-acetylglucosaminyltransferase IVb

Detection Method:
ELISA
Specificity:
Natural and recombinant mouse Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Mouse Mgat4b ELISA Kit
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Mouse Mgat4b ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
N/A


Function:
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.


Subcellular Location:
Golgi apparatus membrane Single-pass type II membrane protein


This product has not yet been referenced specifically in any publications.

[1].
"Kinetic properties and substrate specificities of two recombinant human N-acetylglucosaminyltransferase-IV isozymes."

[2].
"A novel second isoenzyme of the human UDP-N-acetylglucosamine:alpha1,3-D-mannoside beta1,4-N-acetylglucosaminyltransferase family: cDNA cloning, expression, and chromosomal assignment."

[3].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[4].
"N-glycan alterations are associated with drug resistance in human hepatocellular carcinoma."

[5].
"Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer."

[6].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[7].
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."

[8].
"Architecture of the human interactome defines protein communities and disease networks."

[9].
"UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats)."

[10].
"The BioPlex Network: A Systematic Exploration of the Human Interactome."
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