Mgat4b (GeneName), Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (ProteinName), MGT4B_MOUSE.
Mouse Mgat4b/ Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B ELISA Kit
N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb, GlcNAc-T IVb, UDP-N-acetylglucosamine: alpha-1, 3-D-mannoside beta-1, 4-N-acetylglucosaminyltransferase IVb
Natural and recombinant mouse Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.
Golgi apparatus membrane Single-pass type II membrane protein
MRLRNGTFLT | LLLFCLCAFL | SLSWYAALSG | QKGDVVDIYQ | REFLALRDRL |
HAAEQESLKR | SKELNLVLEE | IKRAVSERQA | LRDGEGNRTW | GRLTEDPRLK |
PWNVSHRHVL | HLPTVFHHLP | HLLAKESSLQ | PAVRVGQGRT | GVSVVMGIPS |
VRREVHSYLT | DTLHSLISEL | SPQEKEDSVI | VVLIAETDPQ | YTSAVTENIK |
ALFPTEIHSG | LLEVISPSPH | FYPDFSRLRE | SFGDPKERVR | WRTKQNLDYC |
FLMMYAQSKG | IYYVQLEDDI | VAKPNYLSTM | KNFALQQPSE | DWMILEFSQL |
GFIGKMFKSL | DLSLIVEFIL | MFYRDKPIDW | LLDHILWVKV | CNPEKDAKHC |
DRQKANLRIR | FKPSLFQHVG | THSSLAGKIQ | KLKDKDFGKH | ALRKEHVNPP |
AEVSTSLKTY | QHFTLEKAYL | REDFFWAFTP | AAGDFIRFRF | FQPLRLERFF |
FRSGNIEHPE | DKLFNTSVEV | LPFDNPQSEK | EALQEGRSAT | LRYPRSPDGY |
LQIGSFYKGV | AEGEVDPAFG | PLEALRLSIQ | TDSPVWVILS | EIFLKKAD
This product has not yet been referenced specifically in any publications.
"Kinetic properties and substrate specificities of two recombinant human N-acetylglucosaminyltransferase-IV isozymes."
"A novel second isoenzyme of the human UDP-N-acetylglucosamine:alpha1,3-D-mannoside beta1,4-N-acetylglucosaminyltransferase family: cDNA cloning, expression, and chromosomal assignment."
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
"N-glycan alterations are associated with drug resistance in human hepatocellular carcinoma."
"Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer."
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
"Architecture of the human interactome defines protein communities and disease networks."
"UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats)."
"The BioPlex Network: A Systematic Exploration of the Human Interactome."
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