EIAab
首页  >  酶联免疫试剂盒  >  Rat Mfn2 ELISA Kit
Mfn2 (基因名), Mitofusin-2 (蛋白名), MFN2_RAT.
产品名称:

Rat Mfn2/ Mitofusin-2 ELISA Kit
Mitofusin-2

货号:

E15285r

商标:
EIAab®
监管等级:
别名:

Mitochondrial transmembrane GTPase FZO1A, Transmembrane GTPase MFN2, Protein HSG, Fzo1a

检测方法:
ELISA
特异性:
Natural and recombinant rat Mitofusin-2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Neurosciences
Rat Mfn2 ELISA Kit
规格 & 价格: cart
×
Rat Mfn2 ELISA Kit
邮箱 *
消息 *
Please 登录.
产品说明书
在线询价


通用注释


亚单元:
Forms homomultimers and heteromultimers with MFN1 (PubMed:14561718). Oligomerization is essential for mitochondrion fusion (Probable). Interacts with VAT1 (PubMed:17105775). Interacts with STOML2; may form heterooligomers (By similarity). Interacts (phosphorylated) with PARK2 (By similarity). Interacts with EIF2AK3.


功能:
Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:14561718, PubMed:15322553, PubMed:12589796, PubMed:12598526). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (By similarity). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (PubMed:12598526). Plays an important role in the regulation of vascular smooth muscle cell proliferation (PubMed:15322553). Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria (By similarity). Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress (By similarity). Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.


亚细胞位置:
Mitochondrion outer membrane Multi-pass membrane protein Colocalizes with BAX during apoptosis.


该产品尚未在任何出版物中被引用。
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
通知
new 咨询
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com