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Mfn1 (基因名), Mitofusin-1 (蛋白名), MFN1_MOUSE.
产品名称:

Mouse Mfn1/ Mitofusin-1 ELISA Kit
Mitofusin-1

货号:

E15253m

商标:
EIAab®
监管等级:
别名:

Transmembrane GTPase MFN1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.044ng/mL
特异性:
Natural and recombinant mouse Mitofusin-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Neurosciences
Mouse Mfn1 ELISA Kit
规格 & 价格: cart
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Mouse Mfn1 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Homodimer, also in the absence of bound GTP (By similarity). Forms higher oligomers in the presence of a transition state GTP analog (By similarity). Forms homomultimers and heteromultimers with MFN2 (PubMed:12527753). Oligomerization is essential for mitochondrion fusion (PubMed:15297672). Component of a high molecular weight multiprotein complex (By similarity). Interacts with VAT1.


功能:
Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12527753, PubMed:23921378, PubMed:24513856, PubMed:15297672). Membrane clustering requires GTPase activity (By similarity). It may involve a major rearrangement of the coiled coil domains (PubMed:15297672). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:12527753). Overexpression induces the formation of mitochondrial networks (in vitro). Has low GTPase activity.


亚细胞位置:
Mitochondrion outer membrane Multi-pass membrane protein


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