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首页  >  酶联免疫试剂盒  >  Human MFN1 ELISA Kit
MFN1 (基因名), Mitofusin-1 (蛋白名), MFN1_HUMAN.
产品名称:

Human MFN1/ Mitofusin-1 ELISA Kit
Mitofusin-1

货号:

E15253h

商标:
EIAab®
监管等级:
别名:

Fzo homolog, Transmembrane GTPase MFN1

检测方法:
ELISA
实验类型:
Sandwich
特异性:
Natural and recombinant human Mitofusin-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Neurosciences
Human MFN1 ELISA Kit
规格 & 价格: cart
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Human MFN1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


亚单元:
Homodimer, also in the absence of bound GTP (PubMed:27920125, PubMed:28114303). Forms higher oligomers in the presence of a transition state GTP analog (PubMed:28114303). Forms homomultimers and heteromultimers with MFN2 (By similarity). Oligomerization is essential for mitochondrion fusion (PubMed:27920125, PubMed:28114303). Component of a high molecular weight multiprotein complex (PubMed:12759376). Interacts with VAT1.


功能:
Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12475957, PubMed:12759376, PubMed:27920125, PubMed:28114303). Membrane clustering requires GTPase activity (PubMed:27920125). It may involve a major rearrangement of the coiled coil domains (PubMed:27920125, PubMed:28114303). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:12475957, PubMed:12759376). Overexpression induces the formation of mitochondrial networks (in vitro) (PubMed:12759376). Has low GTPase activity (PubMed:27920125, PubMed:28114303).


亚细胞位置:
Isoform 2 Cytoplasm


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