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Mff (GeneName), Mitochondrial fission factor (ProteinName), MFF_RAT.
Product Name:

Rat Mff/ Mitochondrial fission factor ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Specificity:
Natural and recombinant rat Mitochondrial fission factor
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Cancer
Rat Mff ELISA Kit
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Rat Mff ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Homodimer. Interacts with DNM1L.


Function:
Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.


Subcellular Location:
Mitochondrion outer membrane Single-pass type IV membrane protein Peroxisome Cytoplasmic vesicle Secretory vesicle Synaptic vesicle


This product has not yet been referenced specifically in any publications.

[1].
"The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells."

[2].
"Disturbed mitochondrial and peroxisomal dynamics due to loss of MFF causes Leigh-like encephalopathy, optic atrophy and peripheral neuropathy."

[3].
"Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission."

[4].
"Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission."

[5].
"Potential use of TIA-1, MFF, microRNA-200a-3p, and microRNA-27 as a novel marker for hepatocellular carcinoma."

[6].
"Architecture of the human interactome defines protein communities and disease networks."

[7].
"Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons."

[8].
"Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways."

[9].
"Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family."

[10].
"Distinct Splice Variants of Dynamin-related Protein 1 Differentially Utilize Mitochondrial Fission Factor as an Effector of Cooperative GTPase Activity."
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