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MEX3C (基因名), RNA-binding E3 ubiquitin-protein ligase MEX3C (蛋白名), MEX3C_HUMAN.
产品名称:

Human MEX3C/ RNA-binding E3 ubiquitin-protein ligase MEX3C ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

RING finger and KH domain-containing protein 2, RING finger protein 194, RING-type E3 ubiquitin transferase MEX3C, BM-013, RKHD2, RNF194

检测方法:
ELISA
特异性:
Natural and recombinant human RNA-binding E3 ubiquitin-protein ligase MEX3C
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Epigenetics
Human MEX3C ELISA Kit
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Human MEX3C ELISA Kit
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通用注释


亚单元:
Interacts with USP7, which antagonizes the ability to degrade mRNA.


功能:
E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.


亚细胞位置:
Cytoplasm Nucleus Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. May act as suppressor of replication stress and chromosome missegregation.


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