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Home  >  ELISA Kit  >  Human METRN ELISA Kit
METRN (GeneName), Meteorin (ProteinName), METRN_HUMAN.
Product Name:

Human METRN/ Meteorin ELISA Kit

Cat.#:

E13481h

Brand:
EIAab®
Regulatory Status:
Alternative:

C16orf23, RJD6

Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
15.6-1000pg/mL
Sensitivity:
7.6pg/ml
Specificity:
Natural and recombinant human Meteorin
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
Neurosciences
Human METRN ELISA Kit
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Human METRN ELISA Kit
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Product Datasheets
Datasheet: Down Datasheet
Instruction: Down Instruction
MSDS: MSDS


Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤5.3%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤9.6%

Recovery
Recovery was determined by spiking various levels of Meteorin into serum and plasma.

Sample Type

Average(%)

Recovery Range(%)

Serum

85

80-91

Plasma

87

81-93

 

 

 

 

Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Meteorin and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample

1:2

1:4

1:8

1:16

serum(n=5)

90-101%

83-93%

101-109%

106-117%

EDTA plasma(n=5)

102-114%

83-94%

108-117%

96-106%

heparin plasma(n=5)

104-114%

 

100-109%

93-103%

93-103%

 

General Annotation


Sub Unit:
Monomer.


Function:
Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia.


Subcellular Location:
Secreted


This product has not yet been referenced specifically in any publications.

[1].
"Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension."

[2].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[3].
"The sequence and analysis of duplication-rich human chromosome 16."

[4].
"Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16."

[5].
"Architecture of the human interactome defines protein communities and disease networks."

[6].
"RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination."

[7].
"Maternal Serum Meteorin Levels and the Risk of Preeclampsia."

[8].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[9].
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."
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