Mettl8 (GeneName), Methyltransferase-like protein 8 (ProteinName), METL8_MOUSE.
Mouse Mettl8/ Methyltransferase-like protein 8 ELISA Kit
Tension-induced/inhibited protein, Tip
Natural and recombinant mouse Methyltransferase-like protein 8
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Interacts with EP300.
Probable methyltransferase (By similarity). Isoform 5 overexpression in lung progenitor cells stimulates smooth muscle-specific gene expression and suppresses adipogenic gene expression. Isoform 4 and isoform 7 stimulate adipogenesis.
Cytoplasm Nucleus Isoform 5 localizes to the nucleus upon cell stretch in embryonic lung progenitor cells.
MNVIWRSCIC | RLRQGKVPHR | CQSGVHPVAP | LGSRILTDPA | KVFEHNMWDH |
MQWSKEEEDA | ARKKVEENSA | TRVAPEEQVK | FESDANKYWD | IFYQTHKNKF |
FKNRNWLLRE | FPEILPVNQN | TKEKVGESSW | DQVGSSISRT | QGTETHCQES |
FVSPEPGSRG | RSAPDPDLEE | YSKGPGKTEP | FPGSNATFRI | LEVGCGAGNS |
VFPILNTLQN | IPGSFLYCCD | FASEAVELVK | SHESYSEAQC | SAFIHDVCDD |
GLAYPFPDGI | LDVVLLVFVL | SSIHPDRALF | I
This product has not yet been referenced specifically in any publications.
"TIPs are tension-responsive proteins involved in myogenic versus adipogenic differentiation."
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
"Architecture of the human interactome defines protein communities and disease networks."
"Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans."
"RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination."
"A human interactome in three quantitative dimensions organized by stoichiometries and abundances."
"Multiple loci influencing hippocampal degeneration identified by genome scan."
"Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein."
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
"hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes."
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