MAT1A (GeneName), S-adenosylmethionine synthase isoform type-1 (ProteinName), METK1_BOVIN.
Bovine MAT1A/ S-adenosylmethionine synthase isoform type-1 ELISA Kit
AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1
Natural and recombinant bovine S-adenosylmethionine synthase isoform type-1
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Homotetramer (MAT-I); dimer of dimers. Homodimer (MAT-III).
Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
MNGPVDGLCD | HSLSEEGAFM | FTSESVGEGH | PDKICDQISD | AVLDAHLKQD |
PNAKVACETV | CKTGMVLLCG | EITSMAMVDY | QRVVRETIQH | IGYDDSAKGF |
DFKTCNVLVA | LEQQSPDIAQ | CVHLDRNEED | VGAGDQGLMF | GYATDETEEC |
MPLTIMLAHR | LNARMAELRR | SGQLPWLQPD | SKTQVTVQYT | QDNGAVIPMR |
VHTVVISVQH | NEDITLEDMR | RALKEQVIRA | VVPARYLDED | TIYHLQPSGR |
FVIGGPQGDA | GVTGRKIIVD | TYGGWGAHGG | GAFSGKDYTK | VDRSAAYAAR |
WVAKSLVKAG | LCRRVLVQVS | YAIGVAEPLS | ISIFTYGTSQ | KTERELLDVV |
NKNFDLRPGV | IVRDLDLKKP | IYQKTACYGH | FGRSEFPWEV | PKKLVF
This product has not yet been referenced specifically in any publications.
"Demyelination of the brain is associated with methionine adenosyltransferase I/III deficiency."
"MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate."
"Methionine adenosyltransferase I/III deficiency: novel mutations and clinical variations."
"Dominant inheritance of isolated hypermethioninemia is associated with a mutation in the human methionine adenosyltransferase 1A gene."
"Molecular mechanisms of an inborn error of methionine pathway. Methionine adenosyltransferase deficiency."
"Characterization of a full-length cDNA encoding human liver S-adenosylmethionine synthetase: tissue-specific gene expression and mRNA levels in hepatopathies."
"Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits."
"Human variation in alcohol response is influenced by variation in neuronal signaling genes."
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
"Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia."
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