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MAT1A (GeneName), S-adenosylmethionine synthase isoform type-1 (ProteinName), METK1_BOVIN.
Product Name:

Bovine MAT1A/ S-adenosylmethionine synthase isoform type-1 ELISA Kit

Cat.#:

E0246b

Brand:
EIAab®
Regulatory Status:
Alternative:

AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1

Detection Method:
ELISA
Specificity:
Natural and recombinant bovine S-adenosylmethionine synthase isoform type-1
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Bovine MAT1A ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Homotetramer (MAT-I); dimer of dimers. Homodimer (MAT-III).


Function:
Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.


Subcellular Location:
N/A


This product has not yet been referenced specifically in any publications.

[1].
"Demyelination of the brain is associated with methionine adenosyltransferase I/III deficiency."

[2].
"MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate."

[3].
"Methionine adenosyltransferase I/III deficiency: novel mutations and clinical variations."

[4].
"Dominant inheritance of isolated hypermethioninemia is associated with a mutation in the human methionine adenosyltransferase 1A gene."

[5].
"Molecular mechanisms of an inborn error of methionine pathway. Methionine adenosyltransferase deficiency."

[6].
"Characterization of a full-length cDNA encoding human liver S-adenosylmethionine synthetase: tissue-specific gene expression and mRNA levels in hepatopathies."

[7].
"Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits."

[8].
"Human variation in alcohol response is influenced by variation in neuronal signaling genes."

[9].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[10].
"Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia."
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