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首页  >  酶联免疫试剂盒  >  Chicken METTL14 ELISA Kit
METTL14 (基因名), N6-adenosine-methyltransferase non-catalytic subunit (蛋白名), MET14_CHICK.
产品名称:

Chicken METTL14/ N6-adenosine-methyltransferase non-catalytic subunit ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Methyltransferase-like protein 14, RCJMB04_13h15

检测方法:
ELISA
特异性:
Natural and recombinant chicken N6-adenosine-methyltransferase non-catalytic subunit
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Chicken METTL14 ELISA Kit
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Chicken METTL14 ELISA Kit
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产品说明书


通用注释


亚单元:
Heterodimer; heterodimerizes with METTL3 to form an antiparallel heterodimer that constitutes an active methyltransferase. Component of the WMM complex, a N6-methyltransferase complex composed of a catalytic subcomplex, named MAC, and of an associated subcomplex, named MACOM. The MAC subcomplex is composed of METTL3 and METTL14.


功能:
The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
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