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首页  >  酶联免疫试剂盒  >  Rat Mesd ELISA Kit
Mesd (基因名), LRP chaperone MESD (蛋白名), MESD_RAT.
产品名称:

Rat Mesd/ LRP chaperone MESD ELISA Kit

货号:

E2892r

商标:
EIAab®
监管等级:
别名:

LDLR chaperone MESD, Mesoderm development candidate 2, Mesoderm development protein, Mesdc2

检测方法:
ELISA
特异性:
Natural and recombinant rat LRP chaperone MESD
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Mesd ELISA Kit
规格 & 价格: cart
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Rat Mesd ELISA Kit
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产品说明书


通用注释


亚单元:
Monomer. Interacts with LRP5; the interaction prevents LRP5 from forming aggregates and chaperones LRP6 to the plasma membrane. Interacts with LRP6; the interaction prevents LRP6 from forming aggregates and chaperones LRP6 to the plasma membrane. Interacts with LRP4; the interaction promotes glycosylation of LRP4 and its cell-surface expression.


功能:
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells.


亚细胞位置:
Endoplasmic reticulum Released from apoptotic cells and shed photoreceptor outer segments.


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