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MEPCE (GeneName), 7SK snRNA methylphosphate capping enzyme (ProteinName), MEPCE_HUMAN.
Product Name:

Human MEPCE/ 7SK snRNA methylphosphate capping enzyme ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

MePCE, Bicoid-interacting protein 3 homolog, Bin3 homolog, BCDIN3

Detection Method:
ELISA
Specificity:
Natural and recombinant human 7SK snRNA methylphosphate capping enzyme
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Epigenetics
Human MEPCE ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Component of the 7SK snRNP complex at least composed of P-TEFb (composed of CDK9 and CCNT1/cyclin-T1), HEXIM1, HEXIM2, MEPCE/BCDIN3, SART3 proteins and 7SK and U6 snRNAs.


Function:
S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.


Subcellular Location:
N/A


This product has not yet been referenced specifically in any publications.

[1].
"Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme."

[2].
"Identification and characterization of a novel gene encoding a SEREX antigen in chronic myeloid leukaemia."

[3].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[4].
"Human chromosome 7: DNA sequence and biology."

[5].
"The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression."

[6].
"Architecture of the human interactome defines protein communities and disease networks."

[7].
"Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation."

[8].
"Human METTL16 is a N6-methyladenosine (m6A) methyltransferase that targets pre-mRNAs and various non-coding RNAs."

[9].
"Targeting HIV transcription: the quest for a functional cure."

[10].
"Intermolecular recognition of the non-coding RNA 7SK and HEXIM protein in perspective."
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