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Meox2 (GeneName), Homeobox protein MOX-2 (ProteinName), MEOX2_MOUSE.
Product Name:

Mouse Meox2/ Homeobox protein MOX-2 ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Mesenchyme homeobox 2, Gax, Mox-2, Mox2

Detection Method:
ELISA
Specificity:
Natural and recombinant mouse Homeobox protein MOX-2
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Mouse Meox2 ELISA Kit
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Mouse Meox2 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Interacts with RNF10.


Function:
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.


Subcellular Location:
Nucleus Nucleus speckle


This product has not yet been referenced specifically in any publications.

[1].
"Characterization of Mesenchyme Homeobox 2 (MEOX2) transcription factor binding to RING finger protein 10."

[2].
"Isolation of the human MOX2 homeobox gene and localization to chromosome 7p22.1-p21.3."

[3].
"Molecular cloning and localization of the human GAX gene to 7p21."

[4].
"Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells."

[5].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[6].
"Two candidate tumor suppressor genes, MEOX2 and SOSTDC1, identified in a 7p21 homozygous deletion region in a Wilms tumor."

[7].
"A functional screen for regulators of CKDN2A reveals MEOX2 as a transcriptional activator of INK4a."

[8].
"Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease."

[9].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[10].
"Human chromosome 7: DNA sequence and biology."
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