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MEOX1 (基因名), Homeobox protein MOX-1 (蛋白名), MEOX1_HUMAN.
产品名称:

Human MEOX1/ Homeobox protein MOX-1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Mesenchyme homeobox 1, MOX1

检测方法:
ELISA
特异性:
Natural and recombinant human Homeobox protein MOX-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Human MEOX1 ELISA Kit
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Human MEOX1 ELISA Kit
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通用注释


亚单元:
N/A


功能:
Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.


亚细胞位置:
Nucleus Cytoplasm Localizes predominantly in the nucleus.


该产品尚未在任何出版物中被引用。
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