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Home  >  ELISA Kit  >  Rat Memo1 ELISA Kit
Memo1 (GeneName), Protein MEMO1 (ProteinName), MEMO1_RAT.
Product Name:

Rat Memo1/ Protein MEMO1 ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Mediator of ErbB2-driven cell motility 1, Memo-1

Detection Method:
ELISA
Specificity:
Natural and recombinant rat Protein MEMO1
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Rat Memo1 ELISA Kit
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Rat Memo1 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Interacts with ERBB2 phosphorylated on 'Tyr-1250'.


Function:
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.


Subcellular Location:
N/A


This product has not yet been referenced specifically in any publications.

[1].
"Memo mediates ErbB2-driven cell motility."

[2].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[3].
"Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts."

[4].
"ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells."

[5].
"Memo is homologous to nonheme iron dioxygenases and binds an ErbB2-derived phosphopeptide in its vestigial active site."

[6].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[7].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[8].
"From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map."

[9].
"Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."

[10].
"Architecture of the human interactome defines protein communities and disease networks."
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