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首页  >  酶联免疫试剂盒  >  Mouse Meiob ELISA Kit
Meiob (基因名), Meiosis-specific with OB domain-containing protein (蛋白名), MEIOB_MOUSE.
产品名称:

Mouse Meiob/ Meiosis-specific with OB domain-containing protein ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Protein expressed in male leptotene and zygotene spermatocytes 675, MLZ-675

检测方法:
ELISA
特异性:
Natural and recombinant mouse Meiosis-specific with OB domain-containing protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Meiob ELISA Kit
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Mouse Meiob ELISA Kit
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产品说明书


通用注释


亚单元:
Component of a multiprotein complex with RPA2 and SPATA22.


功能:
Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.


亚细胞位置:
Cytoplasm Nucleus Chromosome Co-localizes with the RPA complex on meiotic chromosome axes. Accumulates on resected DNA. Localization is dependent on SPATA22.


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