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MEGF11 (GeneName), Multiple epidermal growth factor-like domains protein 11 (ProteinName), MEG11_HUMAN.
Product Name:

Human MEGF11/ Multiple epidermal growth factor-like domains protein 11 ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Multiple EGF-like domains protein 11, KIAA1781, UNQ1949/PRO4432

Detection Method:
ELISA
Specificity:
Natural and recombinant human Multiple epidermal growth factor-like domains protein 11
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Human MEGF11 ELISA Kit
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Human MEGF11 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Homopolymer (Probable). Does not interact with MEGF10.


Function:
May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements.


Subcellular Location:
Cell membrane Single-pass type I membrane protein Basolateral cell membrane Single-pass type I membrane protein Forms an irregular, mosaic-like adhesion pattern in region of the cell that becomes firmely fixed to the substrate. Localized to protruding lamellipodia. Does not localize with MEGF10.


This product has not yet been referenced specifically in any publications.

[1].
"Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."

[2].
"Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals."

[3].
"Association of genetic variants with hemorrhagic stroke in Japanese individuals."

[4].
"The mammalian Ced-1 ortholog MEGF10/KIAA1780 displays a novel adhesion pattern."

[5].
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
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