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首页  >  酶联免疫试剂盒  >  Mouse Mef2d ELISA Kit
Mef2d (基因名), Myocyte-specific enhancer factor 2D (蛋白名), MEF2D_MOUSE.
产品名称:

Mouse Mef2d/ Myocyte-specific enhancer factor 2D ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
检测方法:
ELISA
特异性:
Natural and recombinant mouse Myocyte-specific enhancer factor 2D
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Mef2d ELISA Kit
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Mouse Mef2d ELISA Kit
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产品说明书


通用注释


亚单元:
Forms a complex with class II HDACs in undifferentiating cells. On myogenic differentiation, HDACs are released into the cytoplasm allowing MEF2s to interact with other proteins for activation. Interacts with HDAC4 (in undifferentiating cells); the interaction translocates MEF2D to nuclear dots. Forms a heterodimer with MEF2A (By similarity). Interacts with MAPK7; the interaction phosphorylates but does not activate MEF2D (By similarity). Interacts with MYOG. Interacts with CCAR2 and HDAC3.


功能:
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis.


亚细胞位置:
Nucleus Translocated by HDAC4 to nuclear dots.


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