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首页  >  酶联免疫试剂盒  >  Pig MEF2A ELISA Kit
MEF2A (基因名), Myocyte-specific enhancer factor 2A (蛋白名), MEF2A_PIG.
产品名称:

Pig MEF2A/ Myocyte-specific enhancer factor 2A ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
检测方法:
ELISA
特异性:
Natural and recombinant pig Myocyte-specific enhancer factor 2A
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Pig MEF2A ELISA Kit
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Pig MEF2A ELISA Kit
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产品说明书


通用注释


亚单元:
Binds DNA as a homo- or heterodimer (By similarity). Dimerizes with MEF2D. Interacts with HDAC7. Interacts with PIAS1; the interaction enhances sumoylation. Interacts with HDAC4, HDAC9 and SLC2A4RG. Interacts (via the N-terminal) with MAPK7; the interaction results in the phosphorylation and transcriptional activity of MEF2A.


功能:
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
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