027-59234612(+86)
EIAab
Home  >  ELISA Kit  >  Bovine MED7 ELISA Kit
MED7 (GeneName), Mediator of RNA polymerase II transcription subunit 7 (ProteinName), MED7_BOVIN.
Product Name:

Bovine MED7/ Mediator of RNA polymerase II transcription subunit 7 ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Cofactor required for Sp1 transcriptional activation subunit 9, CRSP complex subunit 9, Mediator complex subunit 7, CRSP9

Detection Method:
ELISA
Specificity:
Natural and recombinant bovine Mediator of RNA polymerase II transcription subunit 7
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Bovine MED7 ELISA Kit
Size & Price: Sign In.
×
Bovine MED7 ELISA Kit
Email *
Message *
Please Sign In.
Product Datasheets


General Annotation


Sub Unit:
Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.


Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


Subcellular Location:
Nucleus


This product has not yet been referenced specifically in any publications.

[1].
"The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1."

[2].
"Ubc9 fusion-directed SUMOylation identifies constitutive and inducible SUMOylation."

[3].
"MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription."

[4].
"A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology."

[5].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[6].
"Composite co-activator ARC mediates chromatin-directed transcriptional activation."

[7].
"Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways."

[8].
"Architecture of the human interactome defines protein communities and disease networks."

[9].
"Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase."

[10].
"Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation."
Close
Sample Data
Close
Sample Data
Close
Sample Data
My Cart close
Attention close
History close
Clear All
Comparison close
User
My Cart
Attention
History
Comparison
Top
Message
close_message
Product Name *
Email *
Message: *
Inform
new Message
Size Quantity Price ($) Subtotal 1 ($)
Subtotal 2: $
triangle
Size Quantity Price ($)
Do you want to be our agent and get a lower discount?
Please contact us:
Tel:027-59234612(+86)
Fax:027-59759960(+86)
Email:sales@eiaab.com