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首页  >  酶联免疫试剂盒  >  Human MED6 ELISA Kit
MED6 (基因名), Mediator of RNA polymerase II transcription subunit 6 (蛋白名), MED6_HUMAN.
产品名称:

Human MED6/ Mediator of RNA polymerase II transcription subunit 6 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Activator-recruited cofactor 33 kDa component, ARC33, Mediator complex subunit 6, hMed6, Renal carcinoma antigen NY-REN-28, ARC33

检测方法:
ELISA
特异性:
Natural and recombinant human Mediator of RNA polymerase II transcription subunit 6
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human MED6 ELISA Kit
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Human MED6 ELISA Kit
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产品说明书


通用注释


亚单元:
Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP. Interacts with CTNNB1 and GLI3.


功能:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


亚细胞位置:
Nucleus


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