MED21 (基因名), Mediator of RNA polymerase II transcription subunit 21 (蛋白名), MED21_BOVIN.
Bovine MED21/ Mediator of RNA polymerase II transcription subunit 21 ELISA Kit
Mediator complex subunit 21, RNA polymerase II holoenzyme component SRB7, RNAPII complex component SRB7, SURB7
Natural and recombinant bovine Mediator of RNA polymerase II transcription subunit 21
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP. Interacts with PPARG. Interacts with THRA in a ligand-dependent fashion.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
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