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MECP2 (基因名), Methyl-CpG-binding protein 2 (蛋白名), MECP2_HUMAN.
产品名称:

Human MECP2/ Methyl-CpG-binding protein 2 ELISA Kit
Methyl-CpG-binding蛋白2

货号:

E15238h

商标:
EIAab®
监管等级:
别名:

MeCp-2 protein

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
31.2-2000pg/mL
灵敏度:
10.3pg/mL
特异性:
Natural and recombinant human Methyl-CpG-binding protein 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Neurosciences
Human MECP2 ELISA Kit
规格 & 价格: cart
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Human MECP2 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with FNBP3 (By similarity). Interacts with CDKL5 (PubMed:15917271). Interacts with ATRX; MECP2 recruits ATRX to pericentric heterochromatin in neuronal cells (By similarity). Interacts with NCOR2.


功能:
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).


亚细胞位置:
Nucleus Colocalized with methyl-CpG in the genome.


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