Mdga1 (GeneName), MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (ProteinName), MDGA1_RAT.
Rat Mdga1/ MAM domain-containing glycosylphosphatidylinositol anchor protein 1 ELISA Kit
Natural and recombinant rat MAM domain-containing glycosylphosphatidylinositol anchor protein 1
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Interacts heterophilically through its MAM domain with proteins in axon-rich regions and through its Ig-like domains with proteins in differentiating muscle (By similarity). Interacts (through the Ig-like domains) with NLGN2.
Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity). Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2.
Cell membrane Lipid-anchor GPI-anchor Associated with lipid rafts.
MEVTCLLLLA | LIPFHCRGQG | VYAPAQAQIV | HAGQACVVKE | DNISERVYTI |
RESDTLVLQC | LVTGHPRPQV | RWTKTAGSAS | DKFQETSVFN | ETLRIERIAR |
TQGGRYYCKA | ENGVGVPAIK | SIRVDVQYLD | EPVLTVHQTV | SDVRGNFYQE |
KTVFLRCTVS | SNPPARFIWK | RGSDTLSHSQ | DNGVDIYEPL | YTQGETKVLK |
LKNLRPQDYA | SYTCQVSVRN | VCGIPDKSIT | FQLTNTTAPP | TLKLSVNETL |
VVNPGENVTV | QCLLTGGDPL | PQLHWSHGPG | PLPLGALAQG | GTLSIPSVQA |
RDSGYYNCTA | TNNVGNPAKK | TVNLLVRSLK | NATFQITPDM | IKESENIQLG |
QDLKLSCHVD | AVPQEKVNYQ | WFKNGKPART | SKRLLVTRND | PELPAVTSSL |
ELIDLHFSDY | GTYLCVASFP | GSPVPDLSVE | VNISSETVPP | TISVPKGRAV |
VTVREGSPAE | LQCEVRGKPR | PPVLWSRVDK | EAALLPSGLA | LEETPDGKLR |
VERVSREMSG | TYRCQTARYN | GFNVRAREAQ | VQLTVHFPPE | VEPSSQDVRQ |
ALGRPVLLRC | SLLRGSPQRI | ASAVWRFKGQ | LLPPPPVLPA | AAAEGPDHAE |
LRLDALTRDS | SGNYECSVSN | DVGSATCLFQ | VSAKAYSPEF | YFDTPNPTRS |
HKLSKNYSYV | LQWTQREPDA | VDPVLNYRLS | IRQLNQHNAM | VKAIPVRRVE |
KGQLLEYTLT | DLRVPHSYEI | HLTPYTTFGA | GDMASRVIHY | TEPINSPSLS |
DNTCHFEDEK | ICGYTQDLTD | NFDWTRQNAL | TQNPKRSPNT | GPPTDISGTP |
EGYYMFIETS | RPRELGDRAR | LVSPLYNASA | KFYCVSFFYH | MYGKHIGSLN |
LLVRSRNKGT | LDTHAWSLSG | NKGNVWQQAH | VPINPSGPFQ | IIFEGVRGSG |
YLGDIAIDDV | TLKKGECPRR | QMDPNKVVVM | PGSGAPRLSS | LQLWGSMTIF |
This product has not yet been referenced specifically in any publications.
"Characterization of MDGA1, a novel human glycosylphosphatidylinositol-anchored protein localized in lipid rafts."
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
"WITHDRAWN: Common polymorphisms in the MDGA1 gene are associated with bipolar disorder and schizophrenia in the Chinese Han population."
"Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene."
"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
"Identification and characterization of two novel brain-derived immunoglobulin superfamily members with a unique structural organization."
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
"Genomic organization of a novel glycosylphosphatidylinositol MAM gene expressed in human tissues and tumors."
"Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges."
"Loss of the proprioception and touch sensation channel PIEZO2 in siblings with a progressive form of contractures."
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