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MED12L (基因名), Mediator of RNA polymerase II transcription subunit 12-like protein (蛋白名), MD12L_HUMAN.
产品名称:

Human MED12L/ Mediator of RNA polymerase II transcription subunit 12-like protein ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Mediator complex subunit 12-like protein, Thyroid hormone receptor-associated-like protein, Trinucleotide repeat-containing gene 11 protein-like, PRO0314, KIAA1635, TNRC11L, TRALP, TRALPUSH

检测方法:
ELISA
特异性:
Natural and recombinant human Mediator of RNA polymerase II transcription subunit 12-like protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human MED12L ELISA Kit
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Human MED12L ELISA Kit
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通用注释


亚单元:
May be a component of the Mediator complex, which is known to be composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.


功能:
May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


亚细胞位置:
Nucleus


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