SMCP (GeneName), Sperm mitochondrial-associated cysteine-rich protein (ProteinName), MCSP_HUMAN.
Human SMCP/ Sperm mitochondrial-associated cysteine-rich protein ELISA Kit
Natural and recombinant human Sperm mitochondrial-associated cysteine-rich protein
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida.
Cytoplasm Mitochondrion membrane Peripheral membrane protein Cytoplasmic side Becomes associated with the spermatid mitochondrion capsule at step 16 of spermatogenesis.
This product has not yet been referenced specifically in any publications.
"Isolation, expression, and chromosomal localization of the human mitochondrial capsule selenoprotein gene (MCSP)."
"Comparative genomics of the sperm mitochondria-associated cysteine-rich protein gene."
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
"A proteome-scale map of the human interactome network."
"Ectopically expressed variant form of sperm mitochondria-associated cysteine-rich protein augments tumorigenicity of the stem cell population of lung adenocarcinoma cells."
"Toward a confocal subcellular atlas of the human proteome."
"Function and redox state of mitochondrial localized cysteine-rich proteins important in the assembly of cytochrome c oxidase."
"Non-invasive genetic diagnosis of male infertility using spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization."
"Towards a proteome-scale map of the human protein-protein interaction network."
"Functional interaction of phospholipid hydroperoxide glutathione peroxidase with sperm mitochondrion-associated cysteine-rich protein discloses the adjacent cysteine motif as a new substrate of the selenoperoxidase."
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