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Mcrs1 (基因名), Microspherule protein 1 (蛋白名), MCRS1_MOUSE.
产品名称:

Mouse Mcrs1/ Microspherule protein 1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

58 kDa microspherule protein, Msp58

检测方法:
ELISA
特异性:
Natural and recombinant mouse Microspherule protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Epigenetics
Mouse Mcrs1 ELISA Kit
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Mouse Mcrs1 ELISA Kit
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通用注释


亚单元:
Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the N-terminus of INO80. Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1. Interacts with NOP2. Interacts with PINX1. Interacts with TERT. Interacts with CCDC85B. Interacts with DAXX. Interacts (via N-terminus) with FMR1 (via phosphorylated form). Interacts with FXR1 AND FXR2.


功能:
Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. Binds to G-quadruplex structures in mRNA. Binds to RNA homopolymer poly(G) and poly(U).


亚细胞位置:
Nucleus Nucleus Nucleolus Cytoplasm In microspherules in the nucleolus.


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