ASPA (GeneName), Aspartoacylase (ProteinName), ACY2_PIG.
Product Name:
Pig ASPA/ Aspartoacylase ELISA Kit
Cat.#:
E2260p
Brand:
EIAab®
Regulatory Status:
Alternative:
Aminoacylase-2, ACY-2
Detection Method:
ELISA
Specificity:
Natural and recombinant pig Aspartoacylase
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Homodimer.
Function:
Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter.
Subcellular Location:
Cytoplasm
Nucleus
Database link
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[2].
"Cloning of the human aspartoacylase cDNA and a common missense mutation in Canavan disease."
[3].
"Examination of the mechanism of human brain aspartoacylase through the binding of an intermediate analogue."
[4].
"Identification of the zinc binding ligands and the catalytic residue in human aspartoacylase, an enzyme involved in Canavan disease."
[6].
"Two novel aspartoacylase gene (ASPA) missense mutations specific to Norwegian and Swedish patients with Canavan disease."
[7].
"Identification and characterization of novel mutations of the aspartoacylase gene in non-Jewish patients with Canavan disease."
[8].
"Identification and expression of eight novel mutations among non-Jewish patients with Canavan disease."
[9].
"The molecular basis of canavan (aspartoacylase deficiency) disease in European non-Jewish patients."
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