Home > ELISA Kit > Bovine ACVR1 ELISA Kit

ACVR1 (GeneName), Activin receptor type-1 (ProteinName), ACVR1_BOVIN.

Product Name:

Bovine ACVR1/ Activin receptor type-1 ELISA Kit

Cat.#:

Brand:

EIAab^®

Regulatory Status:

RUO

Alternative:

Activin receptor type I, ACTR-I, Serine/threonine-protein kinase receptor R1, SKR1, ACVRLK2

Detection Method:

ELISA

Specificity:

Natural and recombinant bovine Activin receptor type-1

Sample Type:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

Sample Data:

Research Area:

Cancer

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Bovine ACVR1 ELISA Kit

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Product Datasheets

Data
Citations
Publication
Sequence / 3D
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General Annotation

Sub Unit:

Interacts with FKBP1A. Interacts with FCHO1.

Function:

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May also bind activin.

Subcellular Location:

Membrane Single-pass type I membrane protein

Database link

UniGene:

Bt.16020

SMR:

Q28041

STRING:

9913.ENSBTAP00000015797

Pfam:

PF01064

Uniprot:

Q28041

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Sequence length:

509

Sequence:

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500:

509:

SLDKLKTDC

3D Structure:

Predicted Epitope:

Valid Sequence:

This product has not yet been referenced specifically in any publications.

[1].

"Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity."

(PMID: 8397373)

[2].

"Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1."

(PMID: 19085907)

[3].

"Variants in the ACVR1 gene are associated with AMH levels in women with polycystic ovary syndrome."

(PMID: 18854405)

[4].

"A widely expressed transmembrane serine/threonine kinase that does not bind activin, inhibin, transforming growth factor beta, or bone morphogenic factor."

(PMID: 8389764)

[5].

"An approach based on a genome-wide association study reveals candidate loci for narcolepsy."

(PMID: 20677014)

[6].

"Genetic variation within the hypothalamus-pituitary-ovarian axis in women with recurrent miscarriage."

(PMID: 20716560)

[7].

"A large-scale candidate gene association study of age at menarche and age at natural menopause."

(PMID: 20734064)

[8].

"Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium."

(PMID: 20634197)

[9].

"Mutational screening of ACVR1 gene in Brazilian fibrodysplasia ossificans progressiva patients."

(PMID: 19796185)

[10].

"Novel mutations in ACVR1 result in atypical features in two fibrodysplasia ossificans progressiva patients."

(PMID: 19330033)

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