ACTG1 (GeneName), Actin, cytoplasmic 2 (ProteinName), ACTG_BOVIN.
Product Name:
Bovine ACTG1/ Actin, cytoplasmic 2 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
Gamma-actin, ACTG
Detection Method:
ELISA
Specificity:
Natural and recombinant bovine Actin, cytoplasmic 2
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
Function:
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Subcellular Location:
Cytoplasm
Cytoskeleton
Database link
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"A mutation in the gamma actin 1 (ACTG1) gene causes autosomal dominant hearing loss (DFNA20/26)."
[2].
"Mutations in the gamma-actin gene (ACTG1) are associated with dominant progressive deafness (DFNA20/26)."
[3].
"Novel ACTG1 mutation causing autosomal dominant non-syndromic hearing impairment in a Chinese family."
[5].
"De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome."
[6].
"In vivo and in vitro effects of two novel gamma-actin (ACTG1) mutations that cause DFNA20/26 hearing impairment."
[7].
"Audiometric and vestibular features in a second Dutch DFNA20/26 family with a novel mutation in ACTG1."
[8].
"Beta and gamma-cytoplasmic actins display distinct distribution and functional diversity."
[9].
"Effects of human deafness gamma-actin mutations (DFNA20/26) on actin function."
[10].
"A novel missense mutation in ACTG1 causes dominant deafness in a Norwegian DFNA20/26 family, but ACTG1 mutations are not frequent among families with hereditary hearing impairment."
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