Acta2 (GeneName), Actin, aortic smooth muscle (ProteinName), ACTA_RAT.
Product Name:
Rat Acta2/ Actin, aortic smooth muscle ELISA Kit
Cat.#:
E1342r
Brand:
EIAab®
Regulatory Status:
Alternative:
Alpha-actin-2, Actsa, Actvs
Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
3.12-200ng/mL
Sensitivity:
1.56ng/mL
Specificity:
Natural and recombinant rat Actin, aortic smooth muscle
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
Function:
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Subcellular Location:
Cytoplasm
Cytoskeleton
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease."
[2].
"Mutations in smooth muscle alpha-actin (ACTA2) lead to thoracic aortic aneurysms and dissections."
[3].
"Risk of dissection in thoracic aneurysms associated with mutations of smooth muscle alpha-actin 2 (ACTA2)."
[5].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
[6].
"De novo ACTA2 mutation causes a novel syndrome of multisystemic smooth muscle dysfunction."
[7].
"Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study."
[8].
"Mutation of ACTA2 gene as an important cause of familial and nonfamilial nonsyndromatic thoracic aortic aneurysm and/or dissection (TAAD)."
[9].
"A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease."
[10].
"Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection."
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