Acsl6 (GeneName), Long-chain-fatty-acid--CoA ligase 6 (ProteinName), ACSL6_RAT.
Product Name:
Rat Acsl6/ Long-chain-fatty-acid--CoA ligase 6 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
Acs2, Facl6, Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 6, LACS 6, Long-chain-fatty-acid--CoA ligase, brain isozyme
Detection Method:
ELISA
Specificity:
Natural and recombinant rat Long-chain-fatty-acid--CoA ligase 6
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Cardiovascular
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
N/A
Function:
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:28209804). Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
Subcellular Location:
Mitochondrion outer membrane
Single-pass type III membrane protein
Peroxisome membrane
Single-pass type III membrane protein
Microsome membrane
Single-pass type III membrane protein
Endoplasmic reticulum membrane
Single-pass type III membrane protein
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13)."
[2].
"Identification and molecular characterization of acyl-CoA synthetase in human erythrocytes and erythroid precursors."
[3].
"Acyl-CoA synthetase long-chain family member 6 is associated with premature ovarian failure."
[4].
"Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains."
[5].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
[6].
"Association of haplotypes spanning PDZ-GEF2, LOC728637 and ACSL6 with schizophrenia in Han Chinese."
[7].
"Interaction between interleukin 3 and dystrobrevin-binding protein 1 in schizophrenia."
[9].
"DNA pooling: a comprehensive, multi-stage association analysis of ACSL6 and SIRT5 polymorphisms in schizophrenia."
[10].
"Haplotypes spanning SPEC2, PDZ-GEF2 and ACSL6 genes are associated with schizophrenia."
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