ACSS1 (GeneName), Acetyl-coenzyme A synthetase 2-like, mitochondrial (ProteinName), ACS2L_HUMAN.
Product Name:
Human ACSS1/ Acetyl-coenzyme A synthetase 2-like, mitochondrial ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
Acetate--CoA ligase 2, Acetyl-CoA synthetase 2, AceCS2, Acyl-CoA synthetase short-chain family member 1, ACAS2L, KIAA1846, Propionate--CoA ligase
Detection Method:
ELISA
Specificity:
Natural and recombinant human Acetyl-coenzyme A synthetase 2-like, mitochondrial
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Interacts with SIRT3.
Function:
Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids (PubMed:16788062). Acetate is the preferred substrate (PubMed:16788062). Can also utilize propionate with a much lower affinity (By similarity). Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions (By similarity). Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient (By similarity).
Subcellular Location:
Mitochondrion matrix
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Crystal structures of human SIRT3 displaying substrate-induced conformational changes."
[2].
"Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2."
[3].
"Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals."
[4].
"Association of genetic variants with hemorrhagic stroke in Japanese individuals."
[5].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
[6].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."
[7].
"The importance of acetyl coenzyme A synthetase for 11C-acetate uptake and cell survival in hepatocellular carcinoma."
[8].
"Association of gene polymorphisms with chronic kidney disease in Japanese individuals."
[10].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
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