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首页  >  酶联免疫试剂盒  >  Rat Acot8 ELISA Kit
Acot8 (基因名), Acyl-coenzyme A thioesterase 8 (蛋白名), ACOT8_RAT.
产品名称:

Rat Acot8/ Acyl-coenzyme A thioesterase 8 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Acyl-CoA thioesterase 8, Choloyl-coenzyme A thioesterase, Pte1, Peroxisomal acyl-coenzyme A thioester hydrolase 1, PTE-1, Peroxisomal long-chain acyl-CoA thioesterase 1

检测方法:
ELISA
特异性:
Natural and recombinant rat Acyl-coenzyme A thioesterase 8
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cardiovascular
Rat Acot8 ELISA Kit
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Rat Acot8 ELISA Kit
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产品说明书


通用注释


亚单元:
homodimer.


功能:
Acyl-coenzyme A (acyl-CoA) thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:11785945). Acyl-coenzyme A thioesterase 8/ACOT8 display no strong substrate specificity with respect to the carboxylic acid moiety of Acyl-CoAs. Hydrolyzes medium length (C2 to C20) straight-chain, saturated and unsaturated acyl-CoAS but is inactive towards substrates with longer aliphatic chains (PubMed:11785945). Moreover, it catalyzes the hydrolysis of CoA esters of bile acids, such as choloyl-CoA and chenodeoxycholoyl-CoA and competes with bile acid CoA:amino acid N-acyltransferase (BAAT). ACOT8 is also able to hydrolyze CoA esters of dicarboxylic acids (By similarity). It is involved in the metabolic regulation of peroxisome proliferation (By similarity).


亚细胞位置:
Peroxisome matrix Predominantly localized in the peroxisome but a localization to the cytosol cannot be excluded.


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