ACOT4 (GeneName), Peroxisomal succinyl-coenzyme A thioesterase (ProteinName), ACOT4_HUMAN.
Human ACOT4/ Peroxisomal succinyl-coenzyme A thioesterase ELISA Kit
PTE2B, PTEIB, Acyl-coenzyme A thioesterase 4, Acyl-CoA thioesterase 4, PTE-2b, Peroxisomal acyl coenzyme A thioester hydrolase Ib, Peroxisomal long-chain acyl-CoA thioesterase Ib, PTE-Ib
Natural and recombinant human Peroxisomal succinyl-coenzyme A thioesterase
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:16940157). ACOT4 is a peroxisomal succinyl-coenzyme A thioesterase can also hydrolyze glutaryl-CoA and long chain saturated acyl-CoAs (PubMed:16940157).
MSATLILEPP | GRCCWNEPVR | IAVRGLAPEQ | RVTLRASLRD | EKGALFRAHA |
RYCADARGEL | DLERAPALG | GSFAGLEPMG | LLWALEPEKP | FWRFLKRDVQ |
IPFVVELEVL | DGHDPEPGRL | L CQAQHERH | FLPPGVRRQS | VRAGRVRATL |
FLPPGPGPFP | GIIDIFGIGG | GLLEYRASLL | AG HGFATLA | LAYYNFEDLP |
NNMDNISLEY | FEEAVCYMLQ | HPQVKGPGIG | LLGISLGADI | CLS MASFLK |
NVSATVSING | SGISGNTAIN | YKHSSIPPLG | YDLRRIKVAF | SGLVDIVDIR |
NALV GGYKN | PSMIPIEKAQ | GPILLIVGQD | DHNWRSELYA | QTVSERLQAH |
GKEKPQIICY | PGTGH YIEP | PYFPLCPASL | HRLLNKHVIW | GGEPRAHSKA |
QEDAWKQILA | FFCKHLGGTQ | KTAVPK L
This product has not yet been referenced specifically in any publications.
"Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs."
"A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases."
"The identification of a succinyl-CoA thioesterase suggests a novel pathway for succinate production in peroxisomes."
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
"Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project."
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
"A proteome-wide perspective on peroxisome targeting signal 1(PTS1)-Pex5p affinities."
"Toward a confocal subcellular atlas of the human proteome."
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