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ACO2 (GeneName), Aconitate hydratase, mitochondrial (ProteinName), ACON_PIG.
Product Name:

Pig ACO2/ Aconitate hydratase, mitochondrial ELISA Kit

Cat.#:

E1263p

Brand:
EIAab®
Regulatory Status:
Alternative:

Aconitase, Citrate hydro-lyase

Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
0.156-10ng/mL
Sensitivity:
0.068ng/mL
Specificity:
Natural and recombinant pig Aconitate hydratase, mitochondrial
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
-
Pig ACO2 ELISA Kit
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Product Datasheets
Instruction: Down Instruction
MSDS: MSDS


Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Aconitate hydratase, mitochondrial and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample

1:2

1:4

1:8

1:16

serum(n=5)

104-114%

105-117%

105-114%

101-111%

EDTA plasma(n=5)

109-119%

102-112%

109-120%

108-117%

heparin plasma(n=5)

84-94%

 

114-124%

90-98%

104-115%

 

General Annotation


Sub Unit:
Monomer.


Function:
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.


Subcellular Location:
Mitochondrion


This product has not yet been referenced specifically in any publications.

[1].
"The DNA sequence of human chromosome 22."

[2].
"Characterization of the human mitochondrial aconitase gene (ACO2)."

[3].
"Mutations in the tricarboxylic acid cycle enzyme, aconitase 2, cause either isolated or syndromic optic neuropathy with encephalopathy and cerebellar atrophy."

[4].
"Infantile cerebellar-retinal degeneration associated with a mutation in mitochondrial aconitase, ACO2."

[5].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."

[6].
"A genome annotation-driven approach to cloning the human ORFeome."

[7].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[8].
"Purification and partial amino acid sequence of human aconitase."

[9].
"RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination."

[10].
"A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling."
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