Scd1 (GeneName), Acyl-CoA desaturase 1 (ProteinName), ACOD1_RAT.
Product Name:
Rat Scd1/ Acyl-CoA desaturase 1 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
Delta(9)-desaturase 1, Delta-9 desaturase 1, Fatty acid desaturase 1, Stearoyl-CoA desaturase 1, Scd
Detection Method:
ELISA
Specificity:
Natural and recombinant rat Acyl-CoA desaturase 1
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Sequence / 3D
- Feedback Wall (0)
General Annotation
Sub Unit:
N/A
Function:
Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:2892838, PubMed:7947684). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:2892838, PubMed:7947684). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (PubMed:7947684). Required for normal development of sebaceous glands. Required for the biosynthesis of normal levels of delta-9 unsaturated fatty acids and 1-alkyl-2,3-diacylglycerol in the Harderian gland. Required for normal production of meibum, an oily material that prevents drying of the cornea.
Subcellular Location:
Endoplasmic reticulum membrane
Multi-pass membrane protein
Membrane
Multi-pass membrane protein
Database link
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
This product has not yet been referenced specifically in any publications.
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