Them5 (GeneName), Acyl-coenzyme A thioesterase THEM5 (ProteinName), ACO15_MOUSE.
Product Name:
Mouse Them5/ Acyl-coenzyme A thioesterase THEM5 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
Acyl-CoA thioesterase THEM5, Acyl-coenzyme A thioesterase 15, Thioesterase superfamily member 5, Acot15
Detection Method:
ELISA
Specificity:
Natural and recombinant mouse Acyl-coenzyme A thioesterase THEM5
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Homodimer.
Function:
Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleyl-CoA and other unsaturated long-chain fatty acid-CoA esters. Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin. Required for normal mitochondrial function.
Subcellular Location:
Mitochondrion matrix
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Acyl coenzyme A thioesterase Them5/Acot15 is involved in cardiolipin remodeling and fatty liver development."
[2].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."
[5].
"New genetic associations detected in a host response study to hepatitis B vaccine."
[7].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
[8].
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."
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