Home > ELISA Kit > Mouse Acot13 ELISA Kit

Acot13 (GeneName), Acyl-coenzyme A thioesterase 13 (ProteinName), ACO13_MOUSE.

Product Name:

Mouse Acot13/ Acyl-coenzyme A thioesterase 13 ELISA Kit

Cat.#:

Brand:

EIAab^®

Regulatory Status:

RUO

Alternative:

Acyl-CoA thioesterase 13, Thioesterase superfamily member 2, Them2

Detection Method:

ELISA

Specificity:

Natural and recombinant mouse Acyl-coenzyme A thioesterase 13

Sample Type:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

Sample Data:

Research Area:

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Mouse Acot13 ELISA Kit

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Product Datasheets

Data
Citations
Publication
Sequence / 3D
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General Annotation

Sub Unit:

Homotetramer. Interacts with PCTP.

Function:

Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA (in vitro). May play a role in controlling adaptive thermogenesis.

Subcellular Location:

Cytoplasm Cytosol Mitochondrion Nucleus Cytoplasm Cytoskeleton Spindle During interphase, found both in the nucleus and in the cytoplasm. At mitosis, localizes to the spindle. Colocalizes with tubulin.

Database link

UniGene:

Mm.2125

SMR:

Q9CQR4

STRING:

10090.ENSMUSP00000006900

KEGG:

mmu:66834

Pfam:

PF03061

Uniprot:

Q9CQR4

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Sequence length:

140

Sequence:

50:

100:

140:

VITAHILKQG | KTLAFASVDL | TNKTTGKLIA | QGRHTKHLGN |

3D Model:

3D Structure:

Predicted Epitope:

Valid Sequence:

This product has not yet been referenced specifically in any publications.

[1].

"The mechanisms of human hotdog-fold thioesterase 2 (hTHEM2) substrate recognition and catalysis illuminated by a structure and function based analysis."

(PMID: 19170545)

[2].

"Crystal structure of human thioesterase superfamily member 2."

(PMID: 16934754)

[3].

"Thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (Acot13): a homotetrameric hotdog fold thioesterase with selectivity for long-chain fatty acyl-CoAs."

(PMID: 19405909)

[4].

"Complete sequencing and characterization of 21,243 full-length human cDNAs."

(PMID: 14702039)

[5].

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

(PMID: 15489334)

[6].

"The DNA sequence and analysis of human chromosome 6."

(PMID: 14574404)

[7].

"Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning."