ACOT11 (GeneName), Acyl-coenzyme A thioesterase 11 (ProteinName), ACO11_HUMAN.
Human ACOT11/ Acyl-coenzyme A thioesterase 11 ELISA Kit
Acyl-CoA thioesterase 11, Acyl-CoA thioester hydrolase 11, Adipose-associated thioesterase, Brown fat-inducible thioesterase, BFIT, BFIT, KIAA0707, THEA, Palmitoyl-coenzyme A thioesterase
Natural and recombinant human Acyl-coenzyme A thioesterase 11
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.
Mitochondrion matrix Cytoplasm
MIQNVGNHLR | RGLASVFSNR | TSRKSALRAG | NDSAMADGEG | YRNPTEVQMS |
QLVLPCHTNQ | RGELSVGQL | LKWIDTTACL | SAERHAGCPC | VTASMDDIYF |
EHTISVGQVV | NIKAKVNRAF | N SSMEVGIQ | VASEDLCSEK | QWNVCKALAT |
FVARREITKV | KLKQITPRTE | EEKMEHSVAA | ER RRMRLVY | ADTIKDLLAN |
CAIQGDLESR | DCSRMVPAEK | TRVESVELVL | PPHANHQGNT | FGG QIMAWM |
ENVATIAASR | LCRAHPTLKA | IEMFHFRGPS | QVGDRLVLKA | IVNNAFKHSM |
EVGV CVEAY | RQEAETHRRH | INSAFMTFVV | LDADDQPQLL | PWIRPQPGDG |
ERRYREASAR | KKIRL DRKY | IVSCKQTEVP | LSVPWDPSNQ | VYLSYNNVSS |
LKMLVAKDNW | VLSSEISQVR | LYTLED DKF | LSFHMEMVVH | VDAAQAFLLL |
SDLRQRPEWD | KHYRSVELVQ | QVDEDDAIYH | VTSPALG GH | TKPQDFVILA |
SRRKPCDNGD | PYVIALRSVT | LPTHRETPEY | RRGETLCSGF | CLWREGDQ L |
TKCCWVRVSL | TELVSASGFY | SWGLESRSKG | RRSDGWNGKL | AGGHLSTLKA |
IPVAKINSR | FGYLQDT
This product has not yet been referenced specifically in any publications.
"BFIT, a unique acyl-CoA thioesterase induced in thermogenic brown adipose tissue: cloning, organization of the human gene and assessment of a potential link to obesity."
"Comparative structural analysis of lipid binding START domains."
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
"A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases."
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
"Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
"Architecture of the human interactome defines protein communities and disease networks."
"Thioesterase superfamily member 1 suppresses cold thermogenesis by limiting the oxidation of lipid droplet-derived fatty acids in brown adipose tissue."
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