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首页  >  酶联免疫试剂盒  >  Pig ACMSD ELISA Kit
ACMSD (基因名), 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (蛋白名), ACMSD_PIG.
产品名称:

Pig ACMSD/ 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase ELISA Kit
2-amino-3-carboxymuconate-6-semialdehyde脱羧酶

货号:

E15399p

商标:
EIAab®
监管等级:
别名:

Picolinate carboxylase

检测方法:
ELISA
特异性:
Natural and recombinant pig 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Pig ACMSD ELISA Kit
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产品说明书


通用注释


亚单元:
Monomer.


功能:
Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。

[1].
"Identification and expression of a cDNA encoding human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD). A key enzyme for the tryptophan-niacine pathway and "quinolinate hypothesis"."

[2].
"The crystal structure of human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis."

[3].
"Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies."

[4].
"Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism."

[5].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[6].
"Architecture of the human interactome defines protein communities and disease networks."

[7].
"Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing."

[8].
"An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation."

[9].
"Human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD): a structural and mechanistic unveiling."

[10].
"An atlas of genetic influences on human blood metabolites."
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