CHRM5 (GeneName), Muscarinic acetylcholine receptor M5 (ProteinName), ACM5_HUMAN.
Human CHRM5/ Muscarinic acetylcholine receptor M5 ELISA Kit
Natural and recombinant human Muscarinic acetylcholine receptor M5
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Cell membrane Multi-pass membrane protein Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein
MEGDSYHNAT | TVNGTPVNHQ | PLERHRLWEV | ITIAAVTAVV | SLITIVGNVL |
VMISFKVNSQ | LKTVNNYYLL | SLACADLIIG | IFSMNLYTTY | ILMGRWALGS |
LACDLWLALD | YVASNASVMN | LLVISFDRYF | SITRPLTYRA | KRTPKRAGIM |
IGLAWLISFI | LWAPAILCWQ | YLVGKRTVPL | DECQIQFLSE | PTITFGTAIA |
AFYIPVSVMT | ILYCRIYRET | EKRTKDLADL | QGSDSVTKAE | KRKPAHRALF |
RSCLRCPRPT | LAQRERNQAS | WSSSRRSTST | TGKPSQATGP | SANWAKAEQL |
TTCSSYPSSE | DEDKPATDPV | LQVVYKSQGK | ESPGEEFSAE | ETEETFVKAE |
TEKSDYDTPN | YLLSPAAAHR | PKSQKCVAYK | FRLVVKADGN | QETNNGCHKV |
KIMPCPFPVA | KEPSTKGLNP | NPSHQMTKRK | RVVLVKERKA | AQTLSAILLA |
FIITWTPYNI | MVLVSTFCDK | CVPVTLWHLG | YWLCYVNSTV | NPICYALCNR |
TFRKTFKMLL | LCRWKKKKVE | EKLYWQGNSK | LP
This product has not yet been referenced specifically in any publications.
"A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia."
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
"A common variant in DRD3 receptor is associated with autism spectrum disorder."
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."
"Genetical genomic determinants of alcohol consumption in rats and humans."
"No evidence for association between 19 cholinergic genes and bipolar disorder."
"Linkage of M5 muscarinic and alpha7-nicotinic receptor genes on 15q13 to schizophrenia."
"Upregulation of mRNA encoding the M5 muscarinic acetylcholine receptor in human T- and B-lymphocytes during immunological responses."
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