CHRM4 (GeneName), Muscarinic acetylcholine receptor M4 (ProteinName), ACM4_HUMAN.
Product Name:
Human CHRM4/ Muscarinic acetylcholine receptor M4 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Specificity:
Natural and recombinant human Muscarinic acetylcholine receptor M4
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
N/A
Function:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Cell junction
Synapse
Postsynaptic cell membrane
Multi-pass membrane protein
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."
[3].
"Muscarinic M4 receptor recycling requires a motif in the third intracellular loop."
[4].
"No evidence for association between 19 cholinergic genes and bipolar disorder."
[5].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
[7].
"Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes."
[9].
"Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors."
[10].
"Architecture of the human interactome defines protein communities and disease networks."
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