Chrm3 (GeneName), Muscarinic acetylcholine receptor M3 (ProteinName), ACM3_MOUSE.
Product Name:
Mouse Chrm3/ Muscarinic acetylcholine receptor M3 ELISA Kit
Cat.#:
E1838m
Brand:
EIAab®
Regulatory Status:
Alternative:
Mm3 mAChR, Chrm-3
Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
0.156-10ng/mL
Sensitivity:
0.065ng/mL
Specificity:
Natural and recombinant mouse Muscarinic acetylcholine receptor M3
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Research Area:
Neurosciences
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Homodimer; the dimers can form tetramers (By similarity). Interacts with NALCN (PubMed:19575010).
Function:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Cell junction
Synapse
Postsynaptic cell membrane
Multi-pass membrane protein
Basolateral cell membrane
Multi-pass membrane protein
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Muscarinic M3 receptor stimulation increases cigarette smoke-induced IL-8 secretion by human airway smooth muscle cells."
[2].
"Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy."
[3].
"The muscarinic M3 acetylcholine receptor exists as two differently sized complexes at the plasma membrane."
[4].
"Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up."
[5].
"Muscarinic Acetylcholine Receptor M3 Mutation Causes Urinary Bladder Disease and a Prune-Belly-like Syndrome."
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