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Chrm3 (GeneName), Muscarinic acetylcholine receptor M3 (ProteinName), ACM3_MOUSE.
Product Name:

Mouse Chrm3/ Muscarinic acetylcholine receptor M3 ELISA Kit

Cat.#:

E1838m

Brand:
EIAab®
Regulatory Status:
Alternative:

Mm3 mAChR, Chrm-3

Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
0.156-10ng/mL
Sensitivity:
0.065ng/mL
Specificity:
Natural and recombinant mouse Muscarinic acetylcholine receptor M3
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
Neurosciences
Mouse Chrm3 ELISA Kit
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Mouse Chrm3 ELISA Kit
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Product Datasheets
Datasheet: Down Datasheet
Instruction: Down Instruction
MSDS: MSDS


General Annotation


Sub Unit:
Homodimer; the dimers can form tetramers (By similarity). Interacts with NALCN (PubMed:19575010).


Function:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.


Subcellular Location:
Cell membrane Multi-pass membrane protein Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Basolateral cell membrane Multi-pass membrane protein


This product has not yet been referenced specifically in any publications.

[1].
"Muscarinic M3 receptor stimulation increases cigarette smoke-induced IL-8 secretion by human airway smooth muscle cells."

[2].
"Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy."

[3].
"The muscarinic M3 acetylcholine receptor exists as two differently sized complexes at the plasma membrane."

[4].
"Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up."

[5].
"Muscarinic Acetylcholine Receptor M3 Mutation Causes Urinary Bladder Disease and a Prune-Belly-like Syndrome."
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