Home > ELISA Kit > Human CHRM1 ELISA Kit

CHRM1 (GeneName), Muscarinic acetylcholine receptor M1 (ProteinName), ACM1_HUMAN.

Product Name:

Human CHRM1/ Muscarinic acetylcholine receptor M1 ELISA Kit

Cat.#:

Brand:

EIAab^®

Regulatory Status:

RUO

Detection Method:

ELISA

Specificity:

Natural and recombinant human Muscarinic acetylcholine receptor M1

Sample Type:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

Sample Data:

Research Area:

Neurosciences

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Human CHRM1 ELISA Kit

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Product Datasheets

Data
Citations
Publication
Sequence / 3D
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General Annotation

Sub Unit:

Interacts with GPRASP2.

Function:

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

Subcellular Location:

Cell membrane Multi-pass membrane protein Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein

Database link

UniGene:

Hs.632119

SMR:

P11229

STRING:

9606.ENSP00000306490

KEGG:

hsa:1128

MIM:

118510

Pfam:

PF00001

Uniprot:

P11229

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Sequence length:

460

Sequence:

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460:

SVHRTPSRQC |

3D Structure:

Predicted Epitope:

Valid Sequence:

This product has not yet been referenced specifically in any publications.

[1].

"Muscarinic acetylcholine receptor 1 gene polymorphisms associated with high myopia."

(PMID: 19753311)

[2].

"Gene-based analysis suggests association of the nicotinic acetylcholine receptor beta1 subunit (CHRNB1) and M1 muscarinic acetylcholine receptor (CHRM1) with vulnerability for nicotine dependence."

(PMID: 16874522)

[3].

"Polymorphisms in the muscarinic receptor 1 gene confer susceptibility to asthma in Japanese subjects."

(PMID: 16931638)

[4].

"Muscarinic cholinoceptor activation by pilocarpine triggers apoptosis in human skin fibroblast cells."

(PMID: 19927300)

[5].

"Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?"

(PMID: 20602615)

[6].

"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

(PMID: 20628086)

[7].

"Human variation in alcohol response is influenced by variation in neuronal signaling genes."

(PMID: 20201926)

[8].

"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

(PMID: 19086053)

[9].

"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."

(PMID: 19156168)

[10].

"Genetical genomic determinants of alcohol consumption in rats and humans."

(PMID: 19874574)

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