CHRM1 (GeneName), Muscarinic acetylcholine receptor M1 (ProteinName), ACM1_HUMAN.
Product Name:
Human CHRM1/ Muscarinic acetylcholine receptor M1 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Specificity:
Natural and recombinant human Muscarinic acetylcholine receptor M1
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Interacts with GPRASP2.
Function:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Cell junction
Synapse
Postsynaptic cell membrane
Multi-pass membrane protein
This product has not yet been referenced specifically in any publications.
[1].
"Muscarinic acetylcholine receptor 1 gene polymorphisms associated with high myopia."
[2].
"Gene-based analysis suggests association of the nicotinic acetylcholine receptor beta1 subunit (CHRNB1) and M1 muscarinic acetylcholine receptor (CHRM1) with vulnerability for nicotine dependence."
[3].
"Polymorphisms in the muscarinic receptor 1 gene confer susceptibility to asthma in Japanese subjects."
[4].
"Muscarinic cholinoceptor activation by pilocarpine triggers apoptosis in human skin fibroblast cells."
[5].
"Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?"
[6].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
[7].
"Human variation in alcohol response is influenced by variation in neuronal signaling genes."
[8].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."
[9].
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."
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