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首页  >  酶联免疫试剂盒  >  Rat Acly ELISA Kit
Acly (基因名), ATP-citrate synthase (蛋白名), ACLY_RAT.
产品名称:

Rat Acly/ ATP-citrate synthase ELISA Kit
ATP柠檬酸合成

货号:

E14203r

商标:
EIAab®
监管等级:
别名:

ATP-citrate (pro-S-)-lyase, Citrate cleavage enzyme

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.625-40ng/mL
灵敏度:
0.312ng/mL
特异性:
Natural and recombinant rat ATP-citrate synthase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cardiovascular
Rat Acly ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤4.8%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤7.3%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

101

95-107

Plasma

103

97-109

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

106-117%

89-99%

86-95%

90-99%

EDTA plasma(n=5)

98-107%

86-97%

89-89%

97-108%

heparin plasma(n=5)

90-100%

 

105-117%

85-94%

96-106%

 

通用注释


亚单元:
Homotetramer.


功能:
ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.


亚细胞位置:
Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"Cloning and expression of a human ATP-citrate lyase cDNA."

[2].
"Localization of the gene for ATP citrate lyase (ACLY) distal to gastrin(GAS) and proximal to D17S856 on chromosome 17q12-q21."

[3].
"Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth."

[4].
"ADP-Mg2+ bound to the ATP-grasp domain of ATP-citrate lyase."

[5].
"Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas."

[6].
"Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography."

[7].
"Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study."

[8].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."

[9].
"Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes."

[10].
"ATP-citrate lyase links cellular metabolism to histone acetylation."
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