Chrng (GeneName), Acetylcholine receptor subunit gamma (ProteinName), ACHG_RAT.
Product Name:
Rat Chrng/ Acetylcholine receptor subunit gamma ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
Achrg
Detection Method:
ELISA
Specificity:
Natural and recombinant rat Acetylcholine receptor subunit gamma
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Pentamer of two alpha chains, and one each of the beta, delta, and gamma (in immature muscle) or epsilon (in mature muscle) chains.
Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Location:
Cell junction
Synapse
Postsynaptic cell membrane
Multi-pass membrane protein
Cell membrane
Multi-pass membrane protein
Database link
This product has not yet been referenced specifically in any publications.
[1].
"Escobar syndrome is a prenatal myasthenia caused by disruption of the acetylcholine receptor fetal gamma subunit."
[2].
"Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans."
[3].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."
[4].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."
[5].
"Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes."
[6].
"Nicotinic acetylcholine receptor subunit variants are associated with blood pressure; findings in the Old Order Amish and replication in the Framingham Heart Study."
[7].
"Mutations in the embryonal subunit of the acetylcholine receptor (CHRNG) cause lethal and Escobar variants of multiple pterygium syndrome."
[8].
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
[10].
"Primary structure of the human muscle acetylcholine receptor. cDNA cloning of the gamma and epsilon subunits."
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